| Divisione | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| # | Divisione Centrale | PG | V | VS | SS | P | R | P | Forma |
| 1. | Chicago Fire | 11 | 8 | 1 | 0 | 2 | 22:10 | 27 | |
| 2. | Columbus Crew | 8 | 6 | 1 | 0 | 1 | 22:8 | 21 | |
| 3. | FC Dallas | 11 | 5 | 1 | 0 | 5 | 24:17 | 18 | |
| 4. | Mutiny | 12 | 2 | 0 | 1 | 9 | 14:24 | 6 | |
| # | Divisione Est | PG | V | VS | SS | P | R | P | Forma |
| 1. | Miami | 12 | 10 | 0 | 0 | 2 | 30:18 | 30 | |
| 2. | New York Red Bulls | 12 | 9 | 0 | 0 | 3 | 23:14 | 27 | |
| 3. | DC United | 10 | 6 | 0 | 0 | 4 | 23:16 | 18 | |
| 4. | New England Revolution | 11 | 5 | 1 | 0 | 5 | 21:21 | 18 | |
| # | Divisione Ovest | PG | V | VS | SS | P | R | P | Forma |
| 1. | Los Angeles Galaxy | 12 | 7 | 2 | 0 | 3 | 26:12 | 27 | |
| 2. | Houston Dynamo | 10 | 8 | 0 | 0 | 2 | 24:8 | 24 | |
| 3. | Sporting Kansas City | 12 | 8 | 0 | 1 | 3 | 19:21 | 24 | |
| 4. | Colorado Rapids | 9 | 3 | 0 | 0 | 6 | 14:18 | 9 | |